It is situated above the stomach, right kidney, and intestines on the upper right side of the abdomen, below the diaphragm. The liver is a dark reddish-brown, cone-shaped organ that weighs roughly three pounds. Approximately one pint of the body’s blood supply is always stored in the liver. There are two primary lobes in the liver. These lobules are attached to tiny ducts, which eventually join with bigger ducts to create the hepatic duct. The bile generated by the liver cells is transported to the duodenum and gallbladder through the hepatic duct.
The liver performs many important functions, including:
- Generating bile juice and certain blood plasma proteins
- Converting food into power
- Removing drugs and other poisons from the blood
- Control of blood clotting
Objectives behind the procedure:
People with end-stage liver disease, a major, life-threatening liver malfunction, may be advised to get a liver transplant. Different liver disorders can lead to ESLD. Cirrhosis is the most typical liver condition for which transplants are performed. A fiber-like tissue covering the liver causes cirrhosis, a chronic liver condition that inhibits the removal of toxins and poisons. Other illnesses that can develop into ESLD include but are not restricted to:
- Acute hepatic necrosis: Acute hepatic necrosis is the term used to describe the liver’s tissue dying.
- Biliary atresia: The absence or improper development of the bile ducts is known as biliary atresia.
- Metabolic diseases: Conditions that impair the chemical activity of cells that the liver affects are referred to as metabolic diseases.
- Cancers of the liver: These are primary tumors, meaning they originate in the liver and have not spread elsewhere.
- Autoimmune hepatitis: A persistent liver inflammation that causes the death and damage of liver cells.
Procedure risks include:
It’s possible for difficulties to arise during surgery. The following are just a few potential side effects after liver transplantation:
- occlusion of the young liver’s blood arteries
- Blockage of the bile ducts or bile leakage
- initial inability of replacement liver to operate
Following the transplant, the new liver could not function for a short while. Moreover, the replacement liver can be rejected. The body’s natural response to a foreign item or tissue is rejection. The immune system responds to what it sees as a threat when a new liver is transplanted into a recipient’s body and assaults the new organ, not recognizing the transplanted liver is advantageous. Medication must be administered to deceive the immune system into accepting the transplant and not rejecting it as a foreign item in order for the organ to live in a new body.
Transplantation of the liver is contraindicated in certain circumstances
- Infection that is present or recurrent and cannot be successfully treated
- The spread of cancer. This kind of cancer has spread from its original site to one or more other parts of the body.
- Severe cardiac or other health issues that make it impossible for them to tolerate the surgery
- Serious illnesses that might not get better after transplantation besides liver disease
- Non-adherence to the prescribed course of action
- Drinking alcohol
The Benefits of Liver Transplantation
A healthy liver from another person is substituted for a damaged liver during a liver transplant. The liver might originate from either a living or a deceased donor. A piece of the liver can be donated by family members or unrelated people who are a good match. A live transplant is the name given to this kind of transplant. People who donate a piece of their liver can use the remaining liver to live normal, healthy lives.
You can either transplant your complete liver or only a portion of it. Since the liver is the only organ in the body that has the ability to regenerate, a transplanted piece of liver can function normally again in a few weeks. The liver from the donor is sent in a chilled salt-water solution, which keeps the organ viable for up to 8 hours. Following that, the required tests can be carried out to match the donor with the receiver.
Through a surgical incision in the donor’s upper belly, the replacement liver is extracted. It is inserted into the patient who needs a liver and connected to the bile ducts and blood arteries. The procedure might last up to 12 hours.
Donor criteria for liver
Any family member, including a parent, sibling, child, spouse, or volunteer, is eligible to donate their liver. The requirements for a liver donation consist of:
- Possessing good health.
- Having blood that is compatible with or compatible with the recipient’s blood type
- Being in the age range of 18 and 60
- Being the same size as or larger than the receiver
- Testing is required to make sure the donor is physically fit before they may be a living donor.